Ethan G. Cerami,Christoph Lengauer,Nicolas Stransky
申请号：
US15304656
公开号：
US20170044622A1
申请日:
2015.04.17
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention provides PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) gene fusions, and fragments of those gene fusions. The invention further provides methods of diagnosing and treating diseases or disorders associated with PIK3CA fusions, such as conditions mediated by PIK3CA aberrant expression or activity, or overexpression of PIK3CA.
