THE REGENTS OF THE UNIVERSITY OF COLORADO; A BODY CORPORATE
发明人:
RANDOLPH, THEODORE W.,CLAUSI, AMBER,CARPENTER, JOHN F.,SCHWARTZ, DANIEL K.
申请号：
CA2681567
公开号：
CA2681567C
申请日:
2008.03.18
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The disclosure provides a method of preparing an immunologically-active adjuvant-bound freeze dried vaccine composition. A specific embodiment provides a stable vaccine composition comprising an aluminum-salt adjuvant, a recombinant Clostridium botulinum neurotoxin protein and a glass-forming agent. These vaccine compositions are useful in the treatment of humans and other animals at risk of infection from Clostridium botulinum neurotoxin.
