Theodore Randolph,Amber Clausi,John F. Carpenter,Daniel K. Schwartz
申请号:
US13898249
公开号:
US20130315966A1
申请日:
2013.05.20
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The disclosure provides a method of preparing an immunologically-active adjuvant-bound freeze dried vaccine composition. A specific embodiment provides a stable vaccine composition comprising an aluminum-salt adjuvant, a recombinant Clostridium botulinum neurotoxin protein and a glass-forming agent. These vaccine compositions are useful in the treatment of humans and other animals at risk of infection from Clostridium botulinum neurotoxin.