Theodore W. Randolph,Amber Clausi,John F. Carpenter,Daniel K. Schwartz
申请号：
US12532225
公开号：
US08444991B2
申请日:
2008.03.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The disclosure provides a method of preparing an immunologically-active adjuvant-bound freeze dried vaccine composition. A specific embodiment provides a stable vaccine composition comprising an aluminum-salt adjuvant, a recombinant Clostridium botulinum neurotoxin protein and a glass-forming agent. These vaccine compositions are useful in the treatment of humans and other animals at risk of infection from Clostridium botulinum neurotoxin.
