A waterproof zipper is provided with two halves, each including a half tape member and a row of protruding teeth along an inner edge of the half tape member; and a waterproof layer is secured to an inner surface of the halves. The waterproof layer coated on the inner surfaces of the halves may prevent the liquid from penetrating into the interior of the waterproof zipper, and simplify the structure of the waterproof zipper. A process of manufacturing the waterproof zipper is also provided.