The present invention is characterized in that a mononucleotide includes the nucleoside base for being connected to a sugar, it has a 3 carbon and a 5 carbon, wherein 5 carbon passes through a phosphorus (V) atom of an oxygen atoms bond a to phosphate, and phosphorus (V) atom of the group of a disulphide bio-reversible is (i) bonded to by an oxygen atom (ii) amino that, (a) selectively replaces, the alkoxy selectively replaced, the aryloxy group selectively replaced, or the heteroaryloxy selectively replaced Or (b) pass through the 3 carbon of an oxygen atom. The present invention also conveys mononucleotide to the characterization method of a kind of unit and method, handles a main body with hepatitis C.