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COMPOSITIONS COMPRENANT UN ANTICORPS ET DU MESYLATE DE CAMOSTAT (CM)
专利权人:
GLAXO GROUP LIMITED
发明人:
CLEVELAND, SEAN MATTHEW,SALOMON, STEFAN
申请号:
CA2882223
公开号:
CA2882223A1
申请日:
2013.08.21
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present disclosure provides a means of stabilising an antibody, in particular in protease-rich environments such as the stomach and intestine. A composition, in particular a pharmaceutical composition, comprising an antibody and camostat mesylate is provided, together with uses of said composition as a medicament and in methods of treatment. Compositions of the disclosure are particularly useful in the topical treatment of gastrointestinal conditions, such as Crohn's Disease or ulcerative colitis, or for direct activity in the gut mucosal immune system.
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