Cleveland, sean matthew,Salomon, Stefan,Van Krinks, Cassandra
申请号：
AU2013304627
公开号：
AU2013304627A1
申请日:
2013.08.21
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The present disclosure provides a means of stabilising a single variable domain, in particular in protease-rich environments such as the stomach and intestine. A composition, in particular a pharmaceutical composition, comprising a single variable domain and camostat mesylate is provided, together with uses of said composition as a medicament and in methods of treatment. Compositions of the disclosure are particularly useful in the topical treatment of gastrointestinal conditions, such as Crohns Disease or ulcerative colitis, or for direct activity in the gut mucosal immune system.
