PHOSPHATE SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS

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专利权人:

Merck Sharp & Dohme Corp.

发明人:

Yu Tao,Waddell Sherman T.,McCauley John A.,Graham Thomas H.,Li Hong,Raheem Izzat,Grobler Jay A.

申请号：

US201615560896

公开号：

US2018051043(A1)

申请日:

2016.03.25

申请国别(地区):

美国

年份:

2018

代理人:

摘要：

The present invention relates to Phosphate Substituted Quinolizine Derivatives of Formula (I): and pharmaceutically acceptable salts or prodrug thereof, wherein X, Y, R1, R2, R3, R4, R5, R9 and R10 are as defined herein. The present invention also relates to compositions comprising at least one Phosphate Substituted Quinolizine Derivative, and methods of using the Phosphate Substituted Quinolizine Derivatives for treating or preventing HIV infection in a subject.;

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/