ARYL ETHERS AND USES THEREOF

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专利权人:

INC.;PELOTON THERAPEUTICS

发明人:

DIXON, DARRYL, DAVID,GRINA, JONAS,JOSEY, JOHN, A.,RIZZI, JAMES, P.,SCHLACHTER, STEPHEN, T.,WALLACE, ELI, M.,WANG, BIN,WEHN, PAUL,XU, RUI,YANG, HANBIAO

申请号：

SG11201601616S

公开号：

SG11201601616SA

申请日:

2014.09.05

申请国别(地区):

SG

年份:

2016

代理人:

摘要：

The present disclosure relates to HIF-2a inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2a scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/