A method and system for treating a target area of a patient, for example an area of the brain which includes an occlusion: employ an ultrasound imaging apparatus to produce an ultrasound image of a region of a subject register the ultrasound image to a computed tomography (CT) image dataset identify in the ultrasound image a location of a target area via a marker of the target area produced from the CT image dataset verify the location of the target area with the ultrasound imaging apparatus and provide sonothrombolysis treatment to the target area while monitoring the target area with the ultrasound imaging apparatus.
