A method and system for leading macromolecule substances into target cells includes an image picking unit, an image merging unit, an injection unit, and an energy conversion module. The ultrasound energy conversion module comprises ultrasound transducers or tweeters. The image picking unit is used for picking up the three-dimensional (3D) and the 3D blood vessel photographic images of the tissue or organ where the target cells locate. The image merging unit is used for merging the 3D structure images into the 3D blood vessel photographic images, therefore choosing a blood vessel passage fully covering the target cells for transmitting the macromolecule substances. The injection unit is used for injecting liquid and transmitting the macromolecule substances to the target cells. The energy conversion module is used for exerting energy to activate the liquid to perform biological effects. The energy conversion module comprises ultrasound transducers or tweeters, thereby forming non-permanent holes in the cell membranes of the target cells. The macromolecule substances enter into the target cells through the non-permanent holes.將大分子物質導入標靶細胞之方法及系統係包括影像擷取單元、影像合成單元、注射單元及能量轉換模組。超音波能量轉換模組係包含超音波轉換器或高頻擴音器。影像擷取單元係用於擷取標靶細胞所處之組織或器官的三維(3D)結構影像及3D血管攝影影像。影像合成單元係用以將3D結構影像合併至3D血管攝影影像,從而選擇完全涵蓋用於傳輸大分子物質之標靶細胞的血管通道。注射單元係用於注射液體並傳輸大分子物質至標靶細胞。能量轉換模組係用於施加能量,以活化液體並產生生物效應。能量轉換模組係包含超音波轉換器或高頻擴音器,藉以於標靶細胞之細胞膜中形成非永久性孔洞,以使大分子物質通過非永久性孔進入標靶細胞中。1...將大分子物質導入活體標靶細胞之系統100...影像擷取單元110...影像合成單元120...注射單元130...能量轉換模組140...微處理單元
