含鹽皮質激素受體拮抗劑的藥物組合物及其用途

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专利权人:

山東亨利醫藥科技有限責任公司;KBP BIOSCIENCES CO., LTD.

发明人:

HUANG, Zhenhua,GUO, Xiaocui

申请号：

HK19100983

公开号：

HK1258622A1

申请日:

2019.01.21

申请国别(地区):

HK

年份:

2019

代理人:

摘要：

Provided are a pharmaceutical composition comprising a mineralocorticoid receptor antagonist and use thereof. When the pharmaceutical composition is orally administered to a patient having chronic kidney disease in need thereof, the effective and safe AUC ranges from 188 ngh/mL to 3173 ngh/mL, with bioavailability of 50% or more in mammals. When the pharmaceutical composition is orally administered at a daily dose of 0.1 to 1.0 mg to treat chronic kidney disease, the AUC is controlled at a safe and effective level.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/