A PHARMACEUTICAL COMPOSITION CONTAINING ANTAGONIST OF MINERALOCORTICOID RECEPTORS AND ITS APPLICATION

• 收藏
• 分享

专利权人:

КБП БИОСАЕНСЕС КО.; ЛТД (CN)

发明人:

ХУАН, Чжэньхуа (CN),ГО, Сяоцуй (CN)

申请号：

RU2020120876

公开号：

RU2020120876A

申请日:

2017.09.22

申请国别(地区):

RU

年份:

2020

代理人:

摘要：

Provided are a pharmaceutical composition comprising a mineralocorticoid receptor antagonist and use thereof. When the pharmaceutical composition is orally administered to a patient having chronic kidney disease in need thereof, the effective and safe AUC ranges from 188 ngh/mL to 3173 ngh/mL, with bioavailability of 50% or more in mammals. When the pharmaceutical composition is orally administered at a daily dose of 0.1 to 1.0 mg to treat chronic kidney disease, the AUC is controlled at a safe and effective level.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/