PHARMAZEUTISCHE ZUSAMMENSETZUNG MIT EINEM MINERALKORTIKOID-REZEPTORANTAGONISTEN UND VERWENDUNG DAVON

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专利权人:

KBP Biosciences Co.; Ltd.

发明人:

HUANG, Zhenhua,GUO, Xiaocui

申请号：

EP17852425

公开号：

EP3517113A4

申请日:

2017.09.22

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

Provided are a pharmaceutical composition comprising a mineralocorticoid receptor antagonist and use thereof. When the pharmaceutical composition is orally administered to a patient having chronic kidney disease in need thereof, the effective and safe AUC ranges from 188 ngh/mL to 3173 ngh/mL, with bioavailability of 50% or more in mammals. When the pharmaceutical composition is orally administered at a daily dose of 0.1 to 1.0 mg to treat chronic kidney disease, the AUC is controlled at a safe and effective level.

来源网站：

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来源网址：

http://www.ckcest.cn/home/