Edita Mistiniene,Jonas Henrikas Pesliakas,Milda Pleckaityte,Gintautas Zvirblis
申请号:
US14237807
公开号:
US09243049B2
申请日:
2011.08.09
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to derivatives of recombinant proteins, comprising homo-multimers of genetically fused recombinant biologically active protein monomer units, connected via selected peptide linker moiety and the method of preparation thereof. Derivative of recombinant protein is preferably dimer of human granulocyte colony-stimulating factor, characterised by increased circulation time in vivo.