Adam R. Mezo;Daniel S. Rivera;Robert T. Peters;Alan J. Bitonti;Susan C. Low
发明人:
Robert T. Peters,Adam R. Mezo,Daniel S. Rivera,Alan J. Bitonti,Susan C. Low
申请号：
US12952551
公开号：
US08329182B2
申请日:
2010.11.23
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to a chimeric monomer-dimer hybrid protein wherein the protein comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
