Robert T. Peters,Adam R. Mezo,Daniel S. Rivera,Alan J. Bitonti,Susan C. Low
申请号:
US16518642
公开号:
US20200071385A1
申请日:
2019.07.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to a chimeric monomer-dimer hybrid protein wherein the protein comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.