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Immunoglobulin chimeric monomer-dimer hybrids
专利权人:
Bioverativ Therapeutics Inc.
发明人:
Robert T. Peters,Adam R. Mezo,Daniel S. Rivera,Alan J. Bitoni,Susan C. Low
申请号:
US14530256
公开号:
US09636416B2
申请日:
2014.10.31
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to a chimeric monomer-dimer hybrid protein wherein the protein comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
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