The present invention addresses the problem of providing a compound which has few adverse side effects, high safety and an antagonistic activity to a [mu] opioid receptor. A compound represented by general formula (I) [wherein R1 and R2 may be the same as or different from each other and independently represent a hydrogen atom or a halogen atom (wherein a case in which each of R1 and R2 represents a halogen atom is excluded)； R3 represents a C1-C3 alkyl group or a vinyl group； and R4 represents formula (II) (wherein R5 represents a hydroxy group or a C1-C3 alkoxy group； and R6 and R7 may be the same as or different from each other and independently represent a hydrogen atom or a halogen atom) or formula (III) (wherein the ring A represents a C5-C7 cycloalkyl group which may be substituted by a C1-C3 alkoxy group and is substituted by a halogen atom or a 5- to 7-membered saturated heterocyclic group which is substituted by a halogen atom)] or a pharmacologically acceptable salt thereof.本發明之課題在於提供一種副作用較少、安全性較高之具有μ類鴉片受體拮抗作用之化合物。本發明係一種化合物或其藥理上所容許之鹽，其以下述通式(I)表示：[式中，R1及R2相同或不同，分別表示氫原子或鹵素原子(其中，R1及R2不同時為鹵素原子)，R3表示C1-C3烷基或乙烯基，R4表示式(II)或式(III)，[化2](式中，R5表示羥基或C1-C3烷氧基，R6及R7相同或不同，分別表示氫原子或鹵素原子)(式中，環A表示可經C1-C3烷氧基取代之經鹵素原子取代之C5-C7環烷基；或經鹵素原子取代之5至7員飽和雜環基)]。
