There is provided an endoscope insertion portion capable of illuminating a diseased part corresponding to a part of an endoscope image by irradiation light in an amount approximately the same as that in non-enlarged display, when displaying in an enlarged manner the part of the endoscope image displayed on a display portion of a monitor and the like. The endoscope insertion portion of this invention includes: an insertion portion having a distal end surface; a first illumination optical system for irradiating light onto a subject, which is disposed on the distal end surface; a second illumination optical system for irradiating light onto the subject, which is disposed on the distal end surface; a first image pickup portion including on the distal end surface a first optical member for introducing light from the subject; and a second image pickup portion, which has a higher observation magnification than that of the first observation optical system, including a second optical member for introducing light from the subject, the second optical member being disposed in an area sandwiched by the first illumination optical system and the second illumination optical system.