An endoscope insertion portion capable of illuminating a diseased part corresponding to a part of an endoscope image by irradiation light in an amount approximately the same as that in non-enlarged display, when displaying the part of the endoscope image in an enlarged manner. The endoscope insertion portion of this invention includes: an insertion portion having a distal end surface; a first illumination optical system for irradiating light onto a subject; a second illumination optical system for irradiating light onto the subject; a first image pickup portion including on the distal end surface a first optical member for introducing light from the subject; and a second image pickup portion including a second optical member for introducing light from the subject, the second optical member being disposed in an area sandwiched by the first illumination optical system and the second illumination optical system.