Anti-Siglec-15 antibody

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专利权人:

第一三共株式会社

发明人:

マシュー・スタイブル,ジル・ベルナール・トランブレ,トライアン・シュレア,アンナ・エヌ・モライティス,マリオ・フィリオン

申请号：

JP2015521915

公开号：

JP6268173B2

申请日:

2013.07.17

申请国别(地区):

JP

年份:

2018

代理人:

摘要：

Antibodies and antigen binding fragments that specifically binds to Siglec-15 are described herein. These antibodies or antigen binding fragments may have the ability of inhibiting differentiation of osteoclasts and/or the ability of inhibiting the bone resorption activity of osteoclasts. Compositions and cells expressing anti-Siglec-15 antibodies or antigen binding fragments are also disclosed herewith. Anti-Siglec-15 antibodies may also be useful for the treatment of bone loss, or bone diseases. Methods for the detection or diagnosis of bone loss or bone-related diseases are also described.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/