Salt form or free form, pharmaceutically acceptable N- oxide forms, the compounds of formula (I) inflammatory diseases autoimmune diseases, chronic immune, transplant rejection, malignant neoplastic diseases, angiogenic-related disorders, as well as pharmaceutical compositions comprising novel compound represented by the manufacturing method of said compound, said effective amount of the compound, pain, neurological diseases, viral and use of the compounds in the manufacture of a medicament for the treatment of infectious diseases.遊離形、薬学的に許容される塩形態またはN-オキシド形態の、式(I)で示される新規化合物、該化合物の製造方法、有効量の該化合物を含む医薬組成物、ならびに自己免疫疾患、慢性免疫および炎症性疾患、移植拒絶、悪性新生物性疾患、脈管形成関連障害、疼痛、神経疾患、ウイルス性および感染性疾患の処置のための医薬の製造における該化合物の使用。