The present invention relates to human platelet lysates or enriched fractions of human platelet lysate-derived extracellular vesicles and their use in medicine, in particular inflammatory diseases, neurodegenerative diseases, immune / autoimmune diseases, cardiovascular diseases , An enriched fraction and use for the prevention and / or treatment of skin diseases, orthopedic diseases, tissue regenerative medicine, neoplastic diseases, infectious diseases, transplant rejection, stroke, ischemia or graft versus host disease About. The present invention further comprises the step of adding human platelet lysate or an enriched fraction of human platelet lysate-derived extracellular vesicles to a pharmaceutical preparation or a diagnostic preparation or a cosmetic preparation, a pharmaceutical preparation or a diagnostic preparation or a cosmetic preparation The manufacturing method of 【Selection chart】 None本発明は、ヒト血小板溶解物又はヒト血小板溶解物由来細胞外小胞の富化画分及びそれらの医学における使用に関し、特に、炎症性疾患、神経変性疾患、免疫／自己免疫疾患、心血管疾患、皮膚疾患、整形外科疾患、組織再生医学、腫瘍性疾患、感染性疾患、移植拒絶反応、脳卒中、虚血症又は移植片対宿主病の予防及び／又は治療のための富化画分及び使用に関する。本発明はさらに、ヒト血小板溶解物又はヒト血小板溶解物由来細胞外小胞の富化画分を医薬製剤又は診断製剤又は美容製剤に添加するステップを含んでいる、医薬製剤又は診断製剤又は美容製剤の製造方法に関する。【選択図】なし
