The invention relates to polyphenol derivative compositions for use as preservatives, characterized in that they comprise a combination of at least two derivatives, each of which has general formula (I), where the substituents have the following meanings: - m is an integer from 0 to 9, which is other than 0 if n = 0, - n is an integer from 0 to 9, which is other than 0 if m = 0, - R is: ¦ a hydrogen, ¦ C3-C6 saturated or unsaturated cyclic alcohol, ¦ a sugar residue or oligosaccharide residue, ¦ an acid-alcohol residue, ¦ an aromatic residue, - R1 is: ¦ a hydrogen, ¦ a saturated or unsaturated, linear, branched or cyclic C1-C22 alkyl radical, ¦ a sugar residue or oligosaccharide residue, ¦ an acid-alcohol residue, ¦ an aromatic residue, - R2 is: ¦ a hydrogen, ¦ one or more identical or different substituents, taking up one or more positions on the phenyl group, from among: o saturated or unsaturated, linear, branched or cyclic C1-C22 alkyl, o a sugar ether, o an oligosaccharide residue, o an acid-alcohol ester or ether, o an aromatic ester or ether. Use in the cosmetics industry, in the food industry or in the manufacture of medicaments.