BLACK RONALD,EKMAN LARS,LIEBERBURG IVAN,GRUNDMAN MICHAEL,CALLAWAY JAMES,GREGG KEITH M.,JACOBSEN JACK STEVEN,GILL DAVINDER,TCHISTIAKOVA LIOUDMILA,WIDOM ANGELA
申请号：
NZ62246008
公开号：
NZ622460A
申请日:
2008.10.17
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Disclosed is a humanized form of a mouse 3D6 (Bapineuzumab) antibody comprising three light chain and three heavy chain CDRs of the mouse 3D6 antibody and a human heavy chain in which positions 234, 235 and 237 are occupied by Ala, Ala and Ala respectively, wherein positions are numbered by the EU numbering system and 3D6 is a mouse antibody produced by hybridoma PTA-5130.
