MODIFIED VARIABLE DOMAIN MOLECULES AND METHODS FOR PRODUCING AND USING SAME

• 收藏
• 分享

专利权人:

GARVAN INSTITUTE OF MEDICAL RESEARCH

发明人:

CHRIST, DANIEL,DUDGEON, KIP

申请号：

EP10824324

公开号：

EP2470565A4

申请日:

2010.10.25

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present disclosure provides an isolated protein comprising an antibody heavy chain variable region (VH) comprising a negatively charged amino acid at position 28 and/or 31 and/or 32 and/or 33 and/or 35 according to the numbering system of Kabat, the protein capable of binding specifically to an antigen.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/