LE MOAN NATACHA,KRTOLICA ANA,LEUNG PHILBERTA,CARY STEPHEN P L
申请号：
IN201847033952
公开号：
IN201847033952A
申请日:
2018.09.10
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
The invention provides H-NOX proteins for the delivery of oxygen to hypoxic tissue following stroke. H-NOX proteins extravasate into hypoxic penumbra associated with stroke and preferentially accumulate for sustained delivery of oxygen to the hypoxic tissue to ameliorate adverse affects of stroke related hypoxia. In some embodiments the H-NOX comprises PEGylated H-NOX and non- PEGylated H-NOX.
