LE MOAN Natacha;OMNIOX INC.;KRTOLICA Ana;CARY Stephen P.L.;LEUNG Philberta
发明人:
LE MOAN Natacha,KRTOLICA Ana,LEUNG Philberta,CARY Stephen P.L.
申请号:
IL26117818
公开号:
IL261178D0
申请日:
2018.08.15
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
The invention provides H—NOX proteins for the delivery of oxygen to hypoxic tissue following stroke. H—NOX proteins extravasate into hypoxic penumbra associated with stroke and preferentially accumulate for sustained delivery of oxygen to the hypoxic tissue to ameliorate adverse affects of stroke related hypoxia. In some embodiments, the H—NOX comprises PEGylated H—NOX and non-PEGylated H—NOX.