Shanmugam Srinivasan,Ho Taek Im,Young Su Yoon,Yong Il Kim,Jae Hyun Park,Jong Soo Woo
申请号:
US15300515
公开号:
US09867801B2
申请日:
2015.03.20
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided is an amorphous solid dispersion including a taxane or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable polymer, and a pharmaceutically acceptable surfactant, which has enhanced solubility. Also provided is a method for preparing the solid dispersion. The present subject matter also provides a tablet having good solubility, bioavailability and stability, which comprises the amorphous solid dispersion, an intragranular excipient, and an extragranular excipient.