The invention provides compounds of Formula XXIII: wherein R1 is hydrogen, alkyl, acyl, or silyl, R2 is hydrogen, alkyl, benzyl, acyl, or ester, and R3 is hydrogen, alkyl, an aromatic group, azacyclic, carbocycle, aryl, cycloalkyl, heterocycloalkyl, heterocycle, heteroaryl, heteroalkyl, acyl, or ester, as well as derivatives and stereoisomers, pharmaceutically acceptable salts and derivatives thereof; and methods of making and using such compounds. The invention includes pharmaceutical compositions containing such compounds, and the use of such compounds in methods of treating conditions, diseases, or disorders.本發明提供式XXIII化合物:其中R1係氫、烷基、醯基或矽基,R2係氫、烷基、苄基、醯基或酯,並且R3係氫、烷基、芳族基團、氮雜環、碳環、芳基、環烷基、雜環烷基、雜環、雜芳基、雜烷基、醯基或酯,以及其衍生物及立體異構物、醫藥上可接受之鹽及衍生物;及製造及使用此等化合物之方法。本發明包括含有此等化合物之醫藥組成物,及此等化合物在治療症狀、疾病或病症之方法中之用途。