The invention relates to the use of tetrahydroquinoline derivatives of formula Iwherein R1and R2each independently represent (C1-C4)alkoxy, R3represents aryl-(C1-C4)alkyl or heteroaryl-(C1-C4)alkyl, and R4represents hydrogen or (C1-C4)alkyl, or of pharmaceutically acceptable salts thereof, for the preparation of a medicament for preventing or treating post-traumatic stress disorders.本發明係有關一種化學式I之四氫喹啉衍生物:其中R1與R2分別表示(C1-C4)烷氧基,R3表示芳基-(C1-C4)烷基或者雜芳基-(C1-C4)烷基,R4表示氫或者(C1-C4)烷基,或其醫藥可接受之鹽,用於製備預防或治療創傷後壓迫症之藥劑之用途。