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BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS
专利权人:
ANACOR PHARMACEUTICALS INC.
发明人:
申请号:
IL21775412
公开号:
IL217754A
申请日:
2012.01.26
申请国别(地区):
IL
年份:
2017
代理人:
摘要:
This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent. The compounds have the following formula: wherein X is selected from the group consisting of substituted phenyl, substituted or unsubstituted heteroaryl and unsubstituted cycloalkyl R3a is selected from the group consisting of H1 unsubstituted C1 or C2 or C3 or C4 or C5 or C6 alkyl and unsubstituted C3 or C4 or C5 or C6 cycloalkyl R3b is selected from the group consisting of H, unsubstituted C1 or C2 or C3 or C4 or C5 or C6 alkyl and unsubstituted C3 or C4 or C5 or C6 cycloalkyl with the proviso that R3a and R3b, along with the atom to which they are attached, are optionally joined to form a 3 or 4 or 5 or 6 membered ring, with the proviso that R3a and R3b cannot both be H, or a salt thereof.
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