An adjunct loading system is provided that can include at least one adjunct material configured to be transferred from an adjunct loading member to first and second jaws of an end effector. The loading system can also include a supporting member configured to releasably retain the adjunct material. The loading system can further include an adhesive depot having an adhesive configured to transition from a non-flowable state to a flowable state upon application of heat when the adjunct material is released from the adjunct loading member and transferred to the jaw to retain the adjunct material on the jaw. The adjunct material is released from the adjunct loading member when load is applied thereto. The adhesive depot can be in the form of an adhesive feature formed on a polymer attachment layer or in the form of reservoirs in the supporting member.
