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FORMULE LIQUIDE STABLE
专利权人:
Celltrion Inc.
发明人:
LEE, Joon Won,SHIN, Yeon Kyeong,KANG, Hye Young,KIM, Kwang Woo,KIM, So Young,KIM, Su Jung,OH, Jun Seok,HAN, Won Yong
申请号:
EP18738894
公开号:
EP3569224A4
申请日:
2018.01.10
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Disclosed is a stable liquid formulation, comprising an antibody or antigen-binding portion thereof, an acetate buffer, glycine, and a surfactant, wherein the stable liquid formulation does not comprise at least one of sugar, a sugar alcohol and a metal salt, and the stable liquid formulation is still stable even upon high antibody content, and is superior in osmolality and viscosity, and subcutaneous administration thereof is possible.
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