METHODS OF PREPARING ICOTINIB AND ICOTINIB HYDROCHLORIDE, AND INTERMEDIATES THEREOF

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专利权人:

发明人:

申请号：

EP12846055.7

公开号：

EP2796461B1

申请日:

2012.12.28

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present invention relates to the technical field of medicine. Provided are methods of preparing icotinib, icotinib hydrochloride, and intermediates thereof. The methods avoid the use of phosphoryl chloride, thereby greatly reducing the emission of pollutants, which is of major benefit to the economy and environment.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/