Methods of preparing icotinib and icotinib hydrochloride, and intermediates thereof

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专利权人:

Betta Pharmaceuticals Co.; Ltd

发明人:

Hu, Shaojing,Long, Wei,Wang, Fei,Li, Zongquan

申请号：

AU2012331547

公开号：

AU2012331547C1

申请日:

2012.12.28

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The present invention relates to the technical field of medicine. Provided are methods of preparing icotinib, icotinib hydrochloride, and intermediates thereof. The methods avoid the use of phosphoryl chloride, thereby greatly reducing the emission of pollutants, which is of major benefit to the economy and environment.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/