UNIVERSITETET I TROMSO - NORGES ARKTISKE UNIVERSITET
发明人:
SVENDSEN, JOHN SIGURD,REKDAL, OYSTEIN,EKSTEEN, JOHANNES
申请号：
CA2938705
公开号：
CA2938705A1
申请日:
2015.02.04
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention provides a peptide which: (i) consists of 10 to 16 amino acids (ii) has at least 8 cationic amino acids with either (a) a side chain comprising a guanidinium group, or (b) a side chain comprising an amino group, of which no more than 7 are consecutive and (iii) has 2 or 3 tryptophan residues which are not both, or not all, consecutive, said peptide optionally in the form of a salt, ester or amide, or a peptidomimetic of said peptide. The invention further relates to pharmaceutical compositions containing these compounds, the use of these compounds in therapy, particularly as anti-tumour (e.g. anti-lymphoma) agents and non-therapeutic uses of these compounds.
