Ruxandra Draghia-Akli,Jon Prigge,Niranjan Y. Sardesai,David B. Weiner,Lauren A. Hirao
申请号：
US12473634
公开号：
US08535687B2
申请日:
2009.05.28
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to DNA vaccines that are capable of generating a protective immune response in mammals against a pox virus, and comprises at least one DNA plasmid capable of expressing a plurality of VACV MV antigens, and at least one DNA plasmid capable of expressing a plurality of VACV EV antigens. Also, the present invention relates to methods of inducing a protective immune response in a mammal to pox virus, including a neutralizing antibody response, comprising: injecting into tissue of said mammal said DNA vaccine.
