The method this invention including the process which increases the sutra epithelium electric resistance which leads the decrease of permeability of the cell, dealing with the autoimmunity characteristic disease is offered. Furthermore, the antibody to which the method of dealing with the cicely ACK illness in the individual which needs measures, is offered, as for that method, is directed vis-a-vis single chain zonurin is prescribed, the epithelium growth factor receptor is obstructed with that, and, the process which obstructs PAR is included.< Selective figure > It is not本発明は、細胞の浸透性の減少を導く経上皮電気抵抗を増加させる工程を含む、自己免疫性疾患を処置する方法を提供する。さらに、処置を必要とする個体において、セリアック病を処置する方法が提供され、その方法は、単鎖ゾヌリンに対して向けられた抗体を投与し、それによって上皮成長因子受容体を阻害し、および、PAR2を阻害する工程を含む。【選択図】 なし
