Methods of preventing, inhibiting and/or decreasing protein deposits of a human amyloid protein and/or neuroinflammation in the central nervous system by reducing an amount of exposure to a pathogenic bacterial amyloid in the gastrointestinal tract are disclosed. Also disclosed are methods of preventing, inhibiting and/or treating a proteinopathy by reducing an amount of exposure to a pathogenic bacterial amyloid in the gastrointestinal tract.
