Geoffrey Von Maltzahn,Matthew R. Henn,David N. Cook,David Arthur Berry,Noubar B. Afeyan,Brian Goodman,Mary-Jane Lombardo McKenzie,Marin Vulic
申请号：
US14765810
公开号：
US10064900B2
申请日:
2014.02.04
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Methods and compositions for populating the gastrointestinal tract of a subject are described. Methods include administering to a subject a therapeutic composition comprising a purified population of spore-forming bacteria produced by providing a fecal material and subjecting the material to a treatment step resulting in purification of spore-forming bacteria. Methods include administering an amount effective to engraft and/or augment in the gastrointestinal tract in order to treat or prevent a dysbiosis in the mammalian subject.
