A two-way diagnosis and treatment device capable of connecting blood pressure measurement comprises a power supply unit, a high-voltage diagnosis and treatment unit, an input unit, a microprocessor, a signal conversion unit, a signal transmission unit, an intelligent device, and a blood pressure measuring device, the intelligent device is connected to the signal transmission unit to obtain a diagnosis and treatment signal of the high-voltage diagnosis and treatment unit and is connected to the blood pressure measuring device to obtain a measurement signal, and has an application software for correspondingly processing the diagnosis and treatment signal and displaying a corresponding blood pressure on the intelligent device according to the measurement signal. The application software provides a usage advice on the input unit according to the blood pressure and the diagnosis and treatment signal. The input unit controls the high-voltage diagnosis and treatment unit to perform diagnosis and treatment.