YOO, SANG KU,유상구,CHUNG, JIN WOOK,정진욱,JO, IN GEUN,조인근,KIM, JI YOUNG,김지영,IM, JEONG HO,임정호,KANG, KU SUK,강구석,KIM, JIN YOUNG,김진영,YOO, SANG KUKR,CHUNG, JIN WOOKKR,JO, IN GEUNKR,KIM, JI YOUNGKR,IM, JEONG HOKR,KANG, KU SUKKR,KIM, JIN YOUNGKR
申请号:
KR1020170082391
公开号:
KR1020180002539A
申请日:
2017.06.29
申请国别(地区):
KR
年份:
2018
代理人:
摘要:
The present invention relates to pyranochromenylphenol derivatives having different effects according to directions of optical activity, and a pharmaceutical composition comprising the same. R isomers of the pyranochromenylphenol derivatives have excellent antidiabetic efficacy by inhibiting an increase in blood sugar. S isomers have excellent antiobesity efficacy by inhibiting an increase in the weight.본 발명은 광학활성의 방향에 따라 효능이 상이한 피라노크로메닐페놀 유도체 및 그를 포함하는 약학적 조성물에 관한 것으로, 상기 피라노크로메닐페놀 유도체의 R 이성질체는 혈당의 상승을 억제하여 항당뇨 효능이 우수하며, S 이성질체는 체중의 증가를 억제하여 항비만 효능이 뛰어나다.