Erning Xia,Susan E. Burke,Srini Venkatesh,Vicki Barniak
申请号：
US12203384
公开号：
US08119112B2
申请日:
2008.09.03
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Ophthalmic compositions that comprise 0.1 ppm to 10 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof 0.005 wt. % to 0.15 wt. % of hyaluronic acid and 0.01 wt. % to 1.0 wt. % of an amphoteric surfactant of general formula Iwherein R1 is R or —(CH2)n—NHC(O)R, wherein R is a C8-C16alkyl optionally substituted with hydroxyl and n is 2, 3 or 4 R2 and R3 are each independently selected from methyl, ethyl, propyl or iso-propyl and R4 is a C2-C8alkylene optionally substituted with hydroxyl. The invention is also direct to the use of the ophthalmic compositions to clean and disinfect contact lenses, and in particular, soft, silicone hydrogel contact lenses.
