Erning Xia,Susan E. Burke,Srini Venkatesh,Vicki Barniak,Praveen Tyle
申请号:
US12023509
公开号:
US09096819B2
申请日:
2008.01.31
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Ophthalmic compositions that comprise 0.1 ppm to 50 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof 0.005 wt. % to 2 wt. % of an anionic biopolymer and 0.01 wt. % to 2 wt. % of an amphoteric surfactant of general formula Iwherein R1 is R or —(CH2)n—NHC(O)R, wherein R is a C8-C30alkyl optionally substituted with hydroxyl and n is 2, 3 or 4 R2 and R3 are each independently selected from C1-C4alkyl R4 is a C2-C8alkylene optionally substituted with hydroxyl and Y is CO2− or SO3. The invention is also direct to the use of the ophthalmic compositions to clean and disinfect contact lenses, and in particular, soft, silicone hydrogel contact lenses.