ZUGMAIER, GERHARD,KUFER, PETER,KISCHEL, ROMAN,SUBKLEWE, MARION,KRUPKA, CHRISTINA
申请号:
CA3019740
公开号:
CA3019740A1
申请日:
2017.04.18
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention provides a bispecific construct comprising a first binding domain specifically binding to CD33 and a second binding domain specifically binding to CD3 for use in a method for the treatment of myeloid leukemia, wherein the construct is administered for a maximal period of 14 days followed by a period of at least 14 days without administration of the construct. Moreover, the invention provides a method for the treatment of myeloid leukemia comprising the administration of a therapeutically efficientamount of such bispecific construct and the use of such bispecific construct for the preparation of a pharmaceutical composition for the treatment of myeloid leukemia.