Thomas E. Jenkins,Craig O. Husfeld,Julie D. Seroogy,Jonathan W. Wray
申请号：
US14692526
公开号：
US09585963B2
申请日:
2015.04.21
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Pharmaceutical compositions and their methods of use are provided, where the pharmaceutical compositions comprise an opioid prodrug that provides enzymatically-controlled release of an opioid, and an enzyme inhibitor that interacts with the enzyme(s) that mediates the enzymatically-controlled release of the opioid from the opioid prodrug so as to attenuate enzymatic cleavage of the opioid prodrug.
