Daniel C. Duan;Michael W. Mueting;Stephen W. Stein
发明人:
Michael W. Mueting,Daniel C. Duan,Stephen W. Stein
申请号：
US13001630
公开号：
US09861580B2
申请日:
2009.06.22
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A method of making active pharmaceutical ingredient particles with surface-modified nanoparticles deposited on the particles' surfaces, the method comprising: providing a plurality of media particles having surfaces with the surface-modified nanoparticles deposited on the surfaces； mixing the plurality of media particles with the active ingredient particles, both of which are in dry form, to provide active ingredient particles having surfaces with the surface-modified nanoparticles deposited on the surfaces； and separating the plurality of media particles from the active ingredient particles having surfaces with the surface-modified nanoparticles deposited on the surfaces is disclosed.
